NUR77 (NR4A1) (NM_173157) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC222958L3V
- LentiORF®
Lenti ORF particles, NR4A1 (Myc-DDK-tagged)-Human nuclear receptor subfamily 4, group A, member 1 (NR4A1), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 10,640.00
货期*
详询
规格
Cited in 2 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | NUR77 (NR4A1) (NM_173157) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_173157 |
ORF Size | 1794 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC222958).
|
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_173157.1 |
RefSeq Size | 2542 bp |
RefSeq ORF | 1797 bp |
Locus ID | 3164 |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | MAPK signaling pathway |
MW | 64.5 kDa |
Gene Summary | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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RARβ acts as both an upstream regulator and downstream effector of miR-22, which epigenetically regulates NUR77 to induce apoptosis of colon cancer cells
,null,
The FASEB Journal
,PubMed ID 30252536
[NR4A1]
|
Bile Acids Regulate Nuclear Receptor (Nur77) Expression and Intracellular Location to Control Proliferation and Apoptosis
,null,
Molecular cancer research : MCR
,PubMed ID 25232032
[NR4A1]
|
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