United States
Germany
Japan
United Kingdom
China
TAP2 (NM_018833) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC222668L4V
- LentiORF®
-
Lenti ORF particles, TAP2 (mGFP-tagged) - Human transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (TAP2), transcript variant 2, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 12,540.00
货期*
详询
规格
Product images
经常一起买 (3)
热销推荐Specifications
| Product Data | |
| Product Name | TAP2 (NM_018833) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_018833 |
| ORF Size | 1959 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC222668).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_018833.2, NP_061313.2 |
| RefSeq Size | 2540 bp |
| RefSeq ORF | 1962 bp |
| Locus ID | 6891 |
| Domains | ABC_membrane, ABC_tran, AAA |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters, Antigen processing and presentation, Primary immunodeficiency |
| MW | 71.8 kDa |
| Gene Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
