MYSM1 (NM_001085487) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC220811L4V
- LentiORF®
Lenti ORF particles, MYSM1 (mGFP-tagged) - Human Myb-like, SWIRM and MPN domains 1 (MYSM1), 200ul, >10^7 TU/mL
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CNY 16,815.00
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Specifications
Product Data | |
Product Name | MYSM1 (NM_001085487) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | 2A-DUB; 2ADUB; BMFS4 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001085487 |
ORF Size | 2484 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC220811).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001085487.1 |
RefSeq Size | 2589 bp |
RefSeq ORF | 2487 bp |
Locus ID | 114803 |
Protein Families | Protease |
MW | 94.9 kDa |
Gene Summary | Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation (PubMed:28115216, PubMed:26220525).[UniProtKB/Swiss-Prot Function] |
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