PCDHGB4 (NM_003736) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC219924L3V
- LentiORF®
Lenti ORF particles, PCDHGB4 (Myc-DDK tagged) - Human protocadherin gamma subfamily B, 4 (PCDHGB4), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 16,435.00
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Specifications
Product Data | |
Product Name | PCDHGB4 (NM_003736) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CDH20; FIB2; PCDH-GAMMA-B4 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_003736 |
ORF Size | 2769 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC219924).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003736.2 |
RefSeq Size | 4578 bp |
RefSeq ORF | 2772 bp |
Locus ID | 8641 |
Domains | CA |
MW | 99.93 kDa |
Gene Summary | This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008] |
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