NRAMP1 (SLC11A1) (NM_000578) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC219733L1V
- LentiORF®
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Lenti ORF particles, SLC11A1 (Myc-DDK tagged) - Human solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (SLC11A1), 200ul, >10^7 TU/mL
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CNY 10,070.00
货期*
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规格
Cited in 1 publication. |
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经常一起买 (3)
Specifications
Product Data | |
Product Name | NRAMP1 (SLC11A1) (NM_000578) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | LSH; NRAMP; NRAMP1 |
Vector | pLenti-C-Myc-DDK |
ACCN | NM_000578 |
ORF Size | 1650 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC219733).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_000578.2, NP_000569.2 |
RefSeq Size | 2573 bp |
RefSeq ORF | 1653 bp |
Locus ID | 6556 |
Domains | Nramp |
Protein Families | Transmembrane |
Protein Pathways | Lysosome |
MW | 59.7 kDa |
Gene Summary | This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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The critical role of Nramp1 in degrading α-synuclein oligomers in microglia under iron overload condition.
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Neurobiology of disease
,PubMed ID 28476637
[SLC11A1]
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