GNRHR (NM_001012763) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC218811L3V
- LentiORF®
Lenti ORF particles, GNRHR (Myc-DDK tagged) - Human gonadotropin-releasing hormone receptor (GNRHR), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
Product Data | |
Product Name | GNRHR (NM_001012763) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | GNRHR1; GRHR; HH7; LHRHR; LRHR |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001012763 |
ORF Size | 747 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218811).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001012763.1 |
RefSeq Size | 5715 bp |
RefSeq ORF | 750 bp |
Locus ID | 2798 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | GnRH signaling pathway, Neuroactive ligand-receptor interaction |
MW | 27.5 kDa |
Gene Summary | This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008] |
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