Carboxypeptidase B2 (CPB2) (NM_016413) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC218711L3V
- LentiORF®
-
Lenti ORF particles, CPB2 (Myc-DDK tagged) - Human carboxypeptidase B2 (plasma) (CPB2), transcript variant 2, 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Product Name | Carboxypeptidase B2 (CPB2) (NM_016413) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CPU; PCPB; TAFI |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_016413 |
ORF Size | 1080 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218711).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_016413.2, NP_057497.2 |
RefSeq Size | 1560 bp |
RefSeq ORF | 1082 bp |
Locus ID | 1361 |
Domains | Zn_carbOpept, Propep_M14 |
Protein Families | Druggable Genome, Protease, Secreted Protein |
Protein Pathways | Complement and coagulation cascades |
MW | 40.7 kDa |
Gene Summary | Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] |
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