ST5 (DENND2B) (NM_005418) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC218527L4V
- LentiORF®
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Lenti ORF particles, ST5 (mGFP-tagged) - Human suppression of tumorigenicity 5 (ST5), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 12,540.00
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Specifications
Product Data | |
Product Name | ST5 (DENND2B) (NM_005418) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | HTS1; p126; ST5 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_005418 |
ORF Size | 3411 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218527).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005418.3 |
RefSeq Size | 4571 bp |
RefSeq ORF | 3414 bp |
Locus ID | 6764 |
Domains | DENN, dDENN, uDENN |
MW | 126.3 kDa |
Gene Summary | This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008] |
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