DROSHA (NM_001100412) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC217782L4V

  • LentiORF®

Lenti ORF particles, DROSHA (mGFP-tagged)-Human drosha, ribonuclease type III (DROSHA), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 24,035.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name DROSHA (NM_001100412) Human Tagged ORF Clone Lentiviral Particle
Synonyms ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001100412
ORF Size 4011 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC217782).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001100412.1
RefSeq Size 5389 bp
RefSeq ORF 4014 bp
Locus ID 29102
MW 155.2 kDa
Gene Summary This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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