Rad51L1 (RAD51B) (NM_002877) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC217577L4V
- LentiORF®
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Lenti ORF particles, RAD51B (mGFP-tagged) - Human RAD51-like 1 (S. cerevisiae) (RAD51L1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,740.00
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Specifications
Product Data | |
Product Name | Rad51L1 (RAD51B) (NM_002877) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | R51H2; RAD51L1; REC2 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_002877 |
ORF Size | 1050 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC217577).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_002877.4 |
RefSeq Size | 1875 bp |
RefSeq ORF | 1053 bp |
Locus ID | 5890 |
Domains | AAA |
Protein Families | Druggable Genome |
Protein Pathways | Homologous recombination |
MW | 38.1 kDa |
Gene Summary | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016] |
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