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KPI2 (LMTK2) (NM_014916) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC216097L2V
- LentiORF®
-
Lenti ORF particles, LMTK2 (mGFP-tagged)-Human lemur tyrosine kinase 2 (LMTK2), 200ul, >10^7 TU/mL
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CNY 24,035.00
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Specifications
| Product Data | |
| Product Name | KPI2 (LMTK2) (NM_014916) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | AATYK2; BREK; cprk; hBREK; KPI-2; KPI2; LMR2; PPP1R100 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_014916 |
| ORF Size | 4509 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC216097).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014916.2 |
| RefSeq Size | 5602 bp |
| RefSeq ORF | 4512 bp |
| Locus ID | 22853 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| MW | 164.92 kDa |
| Gene Summary | The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009] |
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