Glycoprotein VI (GP6) (NM_001083899) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC214355L4V
- LentiORF®
Lenti ORF particles, GP6 (mGFP-tagged)-Human glycoprotein VI (platelet) (GP6), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 12,065.00
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Specifications
Product Data | |
Product Name | Glycoprotein VI (GP6) (NM_001083899) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | BDPLT11; GPIV; GPVI |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001083899 |
ORF Size | 1860 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC214355).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001083899.1, NP_001077368.1 |
RefSeq Size | 2268 bp |
RefSeq ORF | 1863 bp |
Locus ID | 51206 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | ECM-receptor interaction |
MW | 67.3 kDa |
Gene Summary | This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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