DECTIN 2 (CLEC6A) (NM_001007033) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC212780L3V
- LentiORF®
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Lenti ORF particles, CLEC6A (Myc-DDK tagged) - Human C-type lectin domain family 6, member A (CLEC6A), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | DECTIN 2 (CLEC6A) (NM_001007033) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | CLEC4N; CLECSF10; dectin-2; hDECTIN-2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001007033 |
ORF Size | 627 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC212780).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001007033.1 |
RefSeq Size | 1613 bp |
RefSeq ORF | 630 bp |
Locus ID | 93978 |
Protein Families | Transmembrane |
MW | 24 kDa |
Gene Summary | The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
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