FAM89B (NM_001098784) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211500L4V

  • LentiORF®

Lenti ORF particles, FAM89B (mGFP-tagged) - Human family with sequence similarity 89, member B (FAM89B), transcript variant 3, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name FAM89B (NM_001098784) Human Tagged ORF Clone Lentiviral Particle
Synonyms LRAP25; MTVR; MTVR1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001098784
ORF Size 462 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC211500).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001098784.1
RefSeq Size 1477 bp
RefSeq ORF 465 bp
Locus ID 23625
Protein Families Druggable Genome
MW 15.2 kDa
Gene Summary Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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