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RAB11 FIP2 (RAB11FIP2) (NM_014904) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC210414L3V
- LentiORF®
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Lenti ORF particles, RAB11FIP2 (Myc-DDK tagged) - Human RAB11 family interacting protein 2 (class I) (RAB11FIP2), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
| Cited in 1 publication. |
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经常一起买 (3)
Specifications
| Product Data | |
| Product Name | RAB11 FIP2 (RAB11FIP2) (NM_014904) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | nRip11; Rab11-FIP2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_014904 |
| ORF Size | 1536 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC210414).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014904.1, NP_055719.1 |
| RefSeq Size | 6077 bp |
| RefSeq ORF | 1539 bp |
| Locus ID | 22841 |
| Domains | C2 |
| Protein Pathways | Endocytosis |
| MW | 58.3 kDa |
| Gene Summary | A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Knockdown Rab11-FIP2 inhibits migration and invasion of nasopharyngeal carcinoma via suppressing Rho GTPase signaling.
,null,
Journal of cellular biochemistry
,PubMed ID 31452257
[RAB11FIP2]
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