SIGLEC8 (NM_014442) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC208582L2V

  • LentiORF®

Lenti ORF particles, SIGLEC8 (mGFP-tagged) - Human sialic acid binding Ig-like lectin 8 (SIGLEC8), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,975.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name SIGLEC8 (NM_014442) Human Tagged ORF Clone Lentiviral Particle
Synonyms SAF2; SIGLEC-8; SIGLEC8L
Vector pLenti-C-mGFP
ACCN NM_014442
ORF Size 1497 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC208582).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_014442.2, NP_055257.2
RefSeq Size 2967 bp
RefSeq ORF 1500 bp
Locus ID 27181
Protein Families Druggable Genome, Transmembrane
MW 54.1 kDa
Gene Summary Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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