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RFX1 (NM_002918) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC207872L3V
- LentiORF®
-
Lenti ORF particles, RFX1 (Myc-DDK tagged) - Human regulatory factor X, 1 (influences HLA class II expression) (RFX1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
| Product Data | |
| Product Name | RFX1 (NM_002918) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | EFC; RFX |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_002918 |
| ORF Size | 2937 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC207872).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_002918.3, NP_002909.3 |
| RefSeq Size | 4392 bp |
| RefSeq ORF | 2940 bp |
| Locus ID | 5989 |
| Protein Families | Druggable Genome |
| MW | 104.7 kDa |
| Gene Summary | This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE). [provided by RefSeq, Jul 2016] |
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