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SLC19A3 (NM_025243) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC206409L4V
- LentiORF®
-
Lenti ORF particles, SLC19A3 (mGFP-tagged) - Human solute carrier family 19, member 3 (SLC19A3), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | SLC19A3 (NM_025243) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | BBGD; THMD2; thTr-2; THTR2 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_025243 |
| ORF Size | 1488 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC206409).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_025243.3 |
| RefSeq Size | 3775 bp |
| RefSeq ORF | 1491 bp |
| Locus ID | 80704 |
| Domains | Folate_carrier |
| Protein Families | Transmembrane |
| MW | 55.7 kDa |
| Gene Summary | This gene encodes a ubiquitously expressed transmembrane thiamine transporter that lacks folate transport activity. Mutations in this gene cause biotin-responsive basal ganglia disease (BBGD); a recessive disorder manifested in childhood that progresses to chronic encephalopathy, dystonia, quadriparesis, and death if untreated. Patients with BBGD have bilateral necrosis in the head of the caudate nucleus and in the putamen. Administration of high doses of biotin in the early progression of the disorder eliminates pathological symptoms while delayed treatment results in residual paraparesis, mild cognitive disability, or dystonia. Administration of thiamine is ineffective in the treatment of this disorder. Experiments have failed to show that this protein can transport biotin. Mutations in this gene also cause a Wernicke's-like encephalopathy.[provided by RefSeq, Jan 2010] |
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