SCAP2 (SKAP2) (NM_003930) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206119L2V
- LentiORF®
Lenti ORF particles, SKAP2 (mGFP-tagged) - Human src kinase associated phosphoprotein 2 (SKAP2), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | SCAP2 (SKAP2) (NM_003930) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | PRAP; RA70; SAPS; SCAP2; SKAP-HOM; SKAP55R |
Vector | pLenti-C-mGFP |
ACCN | NM_003930 |
ORF Size | 1077 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206119).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_003930.3 |
RefSeq Size | 3984 bp |
RefSeq ORF | 1080 bp |
Locus ID | 8935 |
Domains | SH3, PH |
MW | 41.2 kDa |
Gene Summary | The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015] |
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