PHKA2 (NM_000292) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204185L4V

  • LentiORF®

Lenti ORF particles, PHKA2 (mGFP-tagged) - Human phosphorylase kinase, alpha 2 (liver) (PHKA2), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 12,540.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name PHKA2 (NM_000292) Human Tagged ORF Clone Lentiviral Particle
Synonyms GSD9A; PHK; PYK; PYKL; XLG; XLG2
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_000292
ORF Size 3705 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC204185).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_000292.1
RefSeq Size 5325 bp
RefSeq ORF 3708 bp
Locus ID 5256
Protein Families Druggable Genome
Protein Pathways Calcium signaling pathway, Insulin signaling pathway
MW 138.4 kDa
Gene Summary Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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