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NDUFS2 (NM_004550) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC203485L4V
- LentiORF®
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Lenti ORF particles, NDUFS2 (mGFP-tagged) - Human NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (NDUFS2), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL
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Specifications
| Product Data | |
| Product Name | NDUFS2 (NM_004550) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CI-49; MC1DN6 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_004550 |
| ORF Size | 1389 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC203485).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004550.3 |
| RefSeq Size | 2059 bp |
| RefSeq ORF | 1392 bp |
| Locus ID | 4720 |
| Domains | complex1_49Kd |
| Protein Pathways | Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
| MW | 52.5 kDa |
| Gene Summary | The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
Documents
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| FAQs |
| SDS |
