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CTRB1 (NM_001906) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC202806L2V
- LentiORF®
-
Lenti ORF particles, CTRB1 (mGFP-tagged) - Human chymotrypsinogen B1 (CTRB1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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| Product Data | |
| Product Name | CTRB1 (NM_001906) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CTRB |
| Vector | pLenti-C-mGFP |
| ACCN | NM_001906 |
| ORF Size | 789 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC202806).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001906.4 |
| RefSeq Size | 873 bp |
| RefSeq ORF | 792 bp |
| Locus ID | 1504 |
| Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
| MW | 27.9 kDa |
| Gene Summary | This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This CTRB1 gene is located head-to-head with the related CTRB2 gene. Some human populations have an alternate haplotype which inverts a 16.6 Kb region containing portions of intron 1, exon 1, and the upstream sequence of the CTRB1 and CTRB2 genes. In this inversion haplotype exon 1 and flanking sequence is swapped in CTRB1 and CTRB2. This inversion is associated with differential gene expression and increased risk for chronic pancreatitis. The GRCh38 assembly represents the minor allele for SNP rs8048956 of the CTRB1 gene. SNP rs8048956 in intron 1 of the CTRB2 gene is diagnostic for this inversion. This CTRB1 gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Jan 2021] |
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