ARHGAP11A (NM_014783) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC201876L3V
- LentiORF®
Lenti ORF particles, ARHGAP11A (Myc-DDK-tagged)-Human Rho GTPase activating protein 11A (ARHGAP11A), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 11,210.00
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规格
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Specifications
Product Data | |
Product Name | ARHGAP11A (NM_014783) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | GAP (1-12) |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_014783 |
ORF Size | 3069 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC201876).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_014783.2 |
RefSeq Size | 5616 bp |
RefSeq ORF | 3072 bp |
Locus ID | 9824 |
Domains | RhoGAP |
MW | 113.7 kDa |
Gene Summary | This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. This gene also produces a ARHGAP11A-SCG5 readthrough transcript and ARHGAP11A-SCG5 protein. [provided by RefSeq, Feb 2019] |
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