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TTI1 (NM_014657) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC201622L2V
- LentiORF®
-
Lenti ORF particles, TTI1 (mGFP-tagged) - Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), 200ul, >10^7 TU/mL
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CNY 12,540.00
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Specifications
| Product Data | |
| Product Name | TTI1 (NM_014657) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | KIAA0406; smg-10 |
| Vector | pLenti-C-mGFP |
| ACCN | NM_014657 |
| ORF Size | 3267 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201622).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014657.1 |
| RefSeq Size | 3931 bp |
| RefSeq ORF | 3270 bp |
| Locus ID | 9675 |
| MW | 122.1 kDa |
| Gene Summary | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.[UniProtKB/Swiss-Prot Function] |
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