URM1 (NM_030914) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC200854L4V
- LentiORF®
-
Lenti ORF particles, URM1 (mGFP-tagged) - Human ubiquitin related modifier 1 (URM1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | URM1 (NM_030914) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | C9orf74 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_030914 |
ORF Size | 303 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200854).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_030914.1 |
RefSeq Size | 2650 bp |
RefSeq ORF | 306 bp |
Locus ID | 81605 |
MW | 11.4 kDa |
Gene Summary | Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.[UniProtKB/Swiss-Prot Function] |
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