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NDUFA1 (NM_004541) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC200616L3V
- LentiORF®
-
Lenti ORF particles, NDUFA1 (Myc-DDK tagged) - Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (NDUFA1), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | NDUFA1 (NM_004541) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CI-MWFE; MC1DN12; MWFE; ZNF183 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_004541 |
| ORF Size | 210 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC200616).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_004541.2 |
| RefSeq Size | 502 bp |
| RefSeq ORF | 213 bp |
| Locus ID | 4694 |
| Protein Families | Transmembrane |
| Protein Pathways | Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
| MW | 8.1 kDa |
| Gene Summary | The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008] |
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