Trim33 (NM_053170) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR227454L4V

  • LentiORF®

Lenti ORF particles, Trim33 (GFP-tagged) - Mouse tripartite motif-containing 33 (Trim33), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 18,620.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Trim33 (NM_053170) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 8030451N04Rik; AI413936; Ecto; Tif1g
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_053170
ORF Size 3420 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR227454).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_053170.2, NP_444400.2
RefSeq Size 8868 bp
RefSeq ORF 3423 bp
Locus ID 94093
Gene Summary Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway (By similarity). May act as a transcriptional repressor (By similarity). Inhibits the transcriptional response to TGF-beta/BMP signaling cascade (By similarity). Plays a role in the control of cell proliferation (By similarity). Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor. Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade) (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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