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Arnt (NM_009709) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR227373L3V
- LentiORF®
-
Lenti ORF particles, Arnt (Myc-DDK-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator (Arnt), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 12,635.00
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Specifications
| Product Data | |
| Product Name | Arnt (NM_009709) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | bHLHe2; D3Ertd557e; Drnt; ESTM42; Hif1b; mKIAA4051; W08714 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_009709 |
| ORF Size | 2328 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR227373).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009709.4, NP_033839.2 |
| RefSeq Size | 4325 bp |
| RefSeq ORF | 2331 bp |
| Locus ID | 11863 |
| Gene Summary | Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens (By similarity). The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (PubMed:26245371, PubMed:27782878). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28602820).[UniProtKB/Swiss-Prot Function] |
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