Mpz (NM_008623) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR227005L3V
- LentiORF®
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Lenti ORF particles, Mpz (Myc-DDK-tagged) - Mouse myelin protein zero (Mpz), 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
Product Data | |
Product Name | Mpz (NM_008623) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | M; Mpp; P; P-zero; P0 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_008623 |
ORF Size | 744 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227005).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_008623.4, NP_032649.2 |
RefSeq Size | 1993 bp |
RefSeq ORF | 747 bp |
Locus ID | 17528 |
Gene Summary | This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in the orthologous gene in human are associated with myelinating neuropathies. A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Oct 2015] |
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