Fasl (NM_010177) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR226655L4V

  • LentiORF®

Lenti ORF particles, Fasl (GFP-tagged) - Mouse Fas ligand (TNF superfamily, member 6) (Fasl), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet
SDS

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CNY 8,360.00

货期*
详询
规格
    • 200 ul

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经常一起买 (2)
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Specifications

Product Data
Product Name Fasl (NM_010177) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms APT1LG1; CD95-L; CD95L; CD178; Fas-L; Faslg; gld; Tnfsf6; Tnlg1a
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_010177
ORF Size 837 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR226655).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_010177.4, NP_034307.1
RefSeq Size 1935 bp
RefSeq ORF 840 bp
Locus ID 14103
Gene Summary Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:7511063). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494, PubMed:7532682). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed:19794494). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed:10779162). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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