United States
Germany
Japan
United Kingdom
China
Rspo1 (NM_138683) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR226539L3V
- LentiORF®
-
Lenti ORF particles, Rspo1 (Myc-DDK-tagged) - Mouse R-spondin homolog (Xenopus laevis) (Rspo1), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 7,410.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Rspo1 (NM_138683) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | R-spondin; Rspondin |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_138683 |
| ORF Size | 795 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR226539).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_138683.2, NP_619624.2 |
| RefSeq Size | 1834 bp |
| RefSeq ORF | 798 bp |
| Locus ID | 192199 |
| Gene Summary | Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes (PubMed:21693646). Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination (By similarity). Regulates Wnt signaling by antagonizing DKK1/KREM1-mediated internalization of LRP6 through an interaction with KREM1 (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
