Ddx4 (NM_010029) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR226456L4V
- LentiORF®
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Lenti ORF particles, Ddx4 (GFP-tagged) - Mouse DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 (Ddx4), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 13,110.00
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Ddx4 (NM_010029) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AV206478; Mvh; VASA |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_010029 |
ORF Size | 2109 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR226456).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010029.2, NP_034159.1 |
RefSeq Size | 2772 bp |
RefSeq ORF | 2109 bp |
Locus ID | 13206 |
Gene Summary | ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (PubMed:20439430, PubMed:28633017). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (PubMed:20439430, PubMed:28633017). Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (PubMed:20439430, PubMed:28633017). Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (PubMed:28633017).[UniProtKB/Swiss-Prot Function] |
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