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Tlr5 (NM_016928) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR225590L3V
- LentiORF®
-
Lenti ORF particles, Tlr5 (Myc-DDK-tagged) - Mouse toll-like receptor 5 (Tlr5), 200ul, >10^7 TU/mL
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CNY 13,775.00
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Specifications
| Product Data | |
| Product Name | Tlr5 (NM_016928) Mouse Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_016928 |
| ORF Size | 2619 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR225590).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_016928.2, NP_058624.2 |
| RefSeq Size | 3211 bp |
| RefSeq ORF | 2622 bp |
| Locus ID | 53791 |
| Gene Summary | Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life.[UniProtKB/Swiss-Prot Function] |
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