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Hipk1 (NM_010432) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR225509L3V
- LentiORF®
-
Lenti ORF particles, Hipk1 (Myc-DDK-tagged) - Mouse homeodomain interacting protein kinase 1 (Hipk1), 200ul, >10^7 TU/mL
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CNY 17,575.00
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Specifications
| Product Data | |
| Product Name | Hipk1 (NM_010432) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1110062K04Rik; Myak |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_010432 |
| ORF Size | 3633 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR225509).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010432.2, NP_034562.2 |
| RefSeq Size | 8065 bp |
| RefSeq ORF | 3633 bp |
| Locus ID | 15257 |
| Gene Summary | Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.[UniProtKB/Swiss-Prot Function] |
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