Ddb2 (NM_028119) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR225146L4V

LentiORF^®

Lenti ORF particles, Ddb2 (GFP-tagged) - Mouse damage specific DNA binding protein 2 (Ddb2), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet

SDS

Need custom lentivirus service?
Get a free quote

CNY 8,360.00

货期*

详询

规格

Product images

经常一起买 (2)

PS100093V

Lenti ORF control particles of pLenti-C-mGFP-P2A-Puro, >1x10^7 TU/ml, 0.5 ml

CNY 2,950.00

TR30038

One-Wash Lentivirus Titer Kit, HIV-1 p24 ELISA

CNY 5,230.00

Specifications

Product Data
Product Name	Ddb2 (NM_028119) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms	2610043A19Rik
Vector	pLenti-C-mGFP-P2A-Puro
ACCN	NM_028119
ORF Size	1296 bp
Sequence Data	ORF Nucleotide Sequence (showhide) The ORF insert of this clone is exactly the same as(MR225146).
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq	NM_028119.5, NP_082395.2
RefSeq Size	1929 bp
RefSeq ORF	1299 bp
Locus ID	107986
Gene Summary	Required for DNA repair. Binds to DDB1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches. Also appears to function as the substrate recognition module for the DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB1-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1). The DDB1-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage. The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair. The DDB1-CUL4-ROC1 complex also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Product Manuals
TrueORFs: Open Reading Frame Clones - 10 ug in PrecisionShuttle Vector System pLenti-ORF destination vector Transfection - TurboFectin 8.0 Transfection Reagent Plasmid Preparation - PowerPrep Plasmid Purification Kits
FAQs
TrueORF Clones/PrecisionShuttle Organelle Marker Transfection Reagent
SDS
Lenti SDS

Resources

cDNA 克隆相关资源
Video Tutorial: Clone Selection Guide Product Video: What is TrueORF GOLD and why it is the most popular type of clone Video Tutorial: How to make Lentivirus particles Video Tutorial: Is the Lentivirus Safe Product Brochure: cDNA clones $98 Clones. Download the List of 15,000 Protocol: Lentivirus packaging

You may also need

Control Particles

mGFP Antibody

其它Ddb2产品

Expression Plasmids

Lentiviral Particles

CRISPR

RNAi

Proteins

Antibodies