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Acd (NM_001012638) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR224733L3V
- LentiORF®
-
Lenti ORF particles, Acd (Myc-DDK-tagged) - Mouse adrenocortical dysplasia (Acd), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Acd (NM_001012638) Mouse Tagged ORF Clone Lentiviral Particle |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_001012638 |
| ORF Size | 1251 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR224733).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001012638.1 |
| RefSeq Size | 1425 bp |
| RefSeq ORF | 1251 bp |
| Locus ID | 497652 |
| Gene Summary | Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity (By similarity). May play a role in organogenesis (PubMed:15537664).[UniProtKB/Swiss-Prot Function] |
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