Mrap2 (NM_001101482) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR224603L4V
- LentiORF®
Lenti ORF particles, Mrap2 (GFP-tagged) - Mouse melanocortin 2 receptor accessory protein 2 (Mrap2), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Mrap2 (NM_001101482) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | BB633055 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001101482 |
ORF Size | 621 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR224603).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001101482.2, NP_001094952.2 |
RefSeq Size | 1948 bp |
RefSeq ORF | 624 bp |
Locus ID | 244958 |
Gene Summary | Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidence is required in vivo.[UniProtKB/Swiss-Prot Function] |
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