Hmbox1 (NM_177338) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR224083L4V

  • LentiORF®

Lenti ORF particles, Hmbox1 (GFP-tagged) - Mouse homeobox containing 1 (Hmbox1), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Hmbox1 (NM_177338) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms AI451877; AI604847; F830020C16Rik
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_177338
ORF Size 1257 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR224083).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_177338.5
RefSeq Size 2931 bp
RefSeq ORF 1260 bp
Locus ID 219150
Gene Summary Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA (By similarity). Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation (By similarity). Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres (PubMed:23685356). Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs) (By similarity). Enhances formation of telomere C-circles in ALT cells, suggesting a possible role in telomere recombination (By similarity). Might also be involved in the DNA damage response at telomeres (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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