Ube2l3 (NM_009456) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR223806L3V
- LentiORF®
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Lenti ORF particles, Ube2l3 (Myc-DDK-tagged) - Mouse ubiquitin-conjugating enzyme E2L 3 (Ube2l3), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Ube2l3 (NM_009456) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | C79827; Ubce7; UbcM4 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_009456 |
ORF Size | 462 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR223806).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009456.2, NP_033482.1 |
RefSeq Size | 2609 bp |
RefSeq ORF | 465 bp |
Locus ID | 22195 |
Gene Summary | Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.[UniProtKB/Swiss-Prot Function] |
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