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Ppp1r9b (NM_172261) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR222264L4V
- LentiORF®
-
Lenti ORF particles, Ppp1r9b (GFP-tagged) - Mouse protein phosphatase 1, regulatory subunit 9B (Ppp1r9b), 200ul, >10^7 TU/mL
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CNY 14,630.00
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规格
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Specifications
| Product Data | |
| Product Name | Ppp1r9b (NM_172261) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | SPL; Spn |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_172261 |
| ORF Size | 2451 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR222264).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_172261.3, NP_758465.2 |
| RefSeq Size | 4345 bp |
| RefSeq ORF | 2454 bp |
| Locus ID | 217124 |
| Gene Summary | Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1. Required for hepatocyte growth factor (HGF)-induced cell migration (By similarity).[UniProtKB/Swiss-Prot Function] |
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