Spdya (NM_001142631) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR222024L3V
- LentiORF®
Lenti ORF particles, Spdya (Myc-DDK-tagged) - Mouse speedy homolog A (Xenopus laevis) (Spdya), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Spdya (NM_001142631) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 4921517J08Rik; 4930548B21Rik; GS4; MLZ-465; Spdy1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001142631 |
ORF Size | 849 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR222024).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001142631.1, NP_001136103.1 |
RefSeq Size | 1247 bp |
RefSeq ORF | 852 bp |
Locus ID | 70891 |
Gene Summary | Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2 (PubMed:15611625). Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation. Interferes with CDKN1B-mediated inhibition of CDK2. Mediates cell survival during the DNA damage process through activation of CDK2 (By similarity).[UniProtKB/Swiss-Prot Function] |
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