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Lrrc8a (NM_177725) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR221965L4V
- LentiORF®
-
Lenti ORF particles, Lrrc8a (GFP-tagged) - Mouse leucine rich repeat containing 8A (Lrrc8a), 200ul, >10^7 TU/mL
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CNY 14,440.00
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Specifications
| Product Data | |
| Product Name | Lrrc8a (NM_177725) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Lrrc8; mKIAA1437 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_177725 |
| ORF Size | 2430 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR221965).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_177725.4, NP_808393.1 |
| RefSeq Size | 4254 bp |
| RefSeq ORF | 2433 bp |
| Locus ID | 241296 |
| Gene Summary | Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes (PubMed:29769723). The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine (By similarity). Mediates efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress (By similarity). Required for channel activity, together with at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition. Can form functional channels by itself (in vitro) (By similarity). Involved in B-cell development: required for the pro-B cell to pre-B cell transition (PubMed:14660746, PubMed:24752297). Also required for T-cell development (PubMed:24752297).[UniProtKB/Swiss-Prot Function] |
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