United States
Germany
Japan
United Kingdom
China
Gsdma (NM_021347) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR220293L3V
- LentiORF®
-
Lenti ORF particles, Gsdma (Myc-DDK-tagged) - Mouse gasdermin A (Gsdma), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 8,930.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Gsdma (NM_021347) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | BB149167; Gsdm; Gsdm1; Gsdma1; H312E |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_021347 |
| ORF Size | 1338 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR220293).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_021347.4, NP_067322.1 |
| RefSeq Size | 2726 bp |
| RefSeq ORF | 1341 bp |
| Locus ID | 57911 |
| Gene Summary | May promote pyroptosis. Upon cleavage in vitro of genetically engineered GSDMA, the released N-terminal moiety binds to some types of lipids, such as possibly phosphatidylinositol (4,5)-bisphosphate. Homooligomerizes within the membrane and forms pores of 10 -15 nanometers (nm) of inner diameter, triggering cell death. Also binds to bacterial and mitochondrial lipids, including cardiolipin, and exhibits bactericidal activity. The physiological relevance of these observations is unknown.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
