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Eya4 (NM_010167) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR215832L3V
- LentiORF®
-
Lenti ORF particles, Eya4 (Myc-DDK-tagged) - Mouse eyes absent 4 homolog (Drosophila) (Eya4), 200ul, >10^7 TU/mL
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CNY 10,830.00
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Specifications
| Product Data | |
| Product Name | Eya4 (NM_010167) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | B130023L16Rik |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_010167 |
| ORF Size | 1851 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR215832).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010167.4, NP_034297.2 |
| RefSeq Size | 4099 bp |
| RefSeq ORF | 1851 bp |
| Locus ID | 14051 |
| Gene Summary | Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity).[UniProtKB/Swiss-Prot Function] |
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