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Flrt3 (NM_178382) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR215452L4V
- LentiORF®
-
Lenti ORF particles, Flrt3 (GFP-tagged) - Mouse fibronectin leucine rich transmembrane protein 3 (Flrt3), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 12,540.00
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Specifications
| Product Data | |
| Product Name | Flrt3 (NM_178382) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 5530600M07Rik; C430047I10Rik; mKIAA1469 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_178382 |
| ORF Size | 1947 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR215452).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_178382.4, NP_848469.1 |
| RefSeq Size | 3984 bp |
| RefSeq ORF | 1950 bp |
| Locus ID | 71436 |
| Gene Summary | Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners (PubMed:19056886, PubMed:25374360). Plays a role in the spatial organization of brain neurons (PubMed:25374360). Plays a role in vascular development in the retina (PubMed:25374360). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:22405201, PubMed:25374360). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1 (PubMed:24560577). Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (PubMed:21673655, PubMed:25374360). Promotes neurite outgrowth (in vitro) (By similarity). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length (By similarity). Plays a role in the regulation of the density of glutamaergic synapses (PubMed:22405201). Plays a role in fibroblast growth factor-mediated signaling cascades (PubMed:16872596). Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning (PubMed:19056886). Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development (PubMed:18448090). Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (PubMed:19056886).[UniProtKB/Swiss-Prot Function] |
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