Arhgef5 (NM_133674) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR215297L4V

  • LentiORF®

Lenti ORF particles, Arhgef5 (GFP-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 5 (Arhgef5), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 24,225.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Arhgef5 (NM_133674) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 2210412D05Rik; AA717842; AW495314; Tim1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_133674
ORF Size 4743 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR215297).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_133674.1, NP_598435.1
RefSeq Size 5420 bp
RefSeq ORF 4746 bp
Locus ID 54324
Gene Summary Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:19713215, PubMed:21525037). Strongly activates RHOA (PubMed:19713215, PubMed:21525037). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (PubMed:19713215). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:21525037). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (By similarity). Required for SRC-induced podosome formation (PubMed:21525037). Involved in positive regulation of immature dendritic cell migration (PubMed:19713215).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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