Cux1 (NM_009986) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR211983L3V
- LentiORF®
Lenti ORF particles, Cux1 (Myc-DDK-tagged) - Mouse cut-like homeobox 1 (Cux1), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 20,045.00
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Specifications
Product Data | |
Product Name | Cux1 (NM_009986) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | CDP; Cutl1; Cux; Cux-1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_009986 |
ORF Size | 4278 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR211983).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_009986.4, NP_034116.3 |
RefSeq Size | 12912 bp |
RefSeq ORF | 4281 bp |
Locus ID | 13047 |
Gene Summary | Transcription factor involved in the control of neuronal differentiation in the brain. Regulates dendrite development and branching, and dendritic spine formation in cortical layers II-III (PubMed:20510857). Also involved in the control of synaptogenesis (Probable). In addition, it has probably a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator.[UniProtKB/Swiss-Prot Function] |
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