United States
Germany
Japan
United Kingdom
China
Ankrd27 (BC065093) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR211401L4V
- LentiORF®
-
Lenti ORF particles, Ankrd27 (GFP-tagged) - Mouse ankyrin repeat domain 27 (VPS9 domain) (cDNA clone MGC:85985 IMAGE:6855501), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 13,205.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Ankrd27 (BC065093) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | MGC25907, Varp |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC065093 |
| ORF Size | 2979 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR211401).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC065093, AAH65093 |
| RefSeq Size | 4105 bp |
| RefSeq ORF | 2981 bp |
| Locus ID | 245886 |
| Gene Summary | May be a guanine exchange factor (GEF) for Rab21, Rab32 and Rab38 and regulate endosome dynamics (By similarity). May regulate the participation of VAMP7 in membrane fusion events; in vitro inhibits VAMP7-mediated SNARE complex formation by trapping VAMP7 in a closed, fusogenically inactive conformation (By similarity). Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with Rab32, Rab38 and VAMP7 (PubMed:19403694, PubMed:21187289). Involved in the regulation of neurite growth; the function seems to require its GEF activity, probably towards Rab21, and VAMP7 but not Rab32/38 (PubMed:19745841, PubMed:22171327). Proposed to be involved in Golgi sorting of VAMP7 and transport of VAMP7 vesicles to the cell surface; the function seems to implicate kinesin heavy chain isoform 5 proteins, GOLGA4, RAB21 and MACF1. Required for the colocalization of VAMP7 and Rab21, probably on TGN sites (By similarity). Involved in GLUT1 endosome-to-plasma membrane trafficking; the function is dependent of association with VPS29 (By similarity). Regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (PubMed:26620560).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
其它Ankrd27产品
Customer
Reviews
Loading...
