Arhgef1 (NM_001130152) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR211176L4V

  • LentiORF®

Lenti ORF particles, Arhgef1 (GFP-tagged) - Mouse Rho guanine nucleotide exchange factor (GEF) 1 (Arhgef1), transcript variant 3, 200ul, >10^7 TU/mL

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CNY 15,960.00

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规格
    • 200 ul

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Specifications

Product Data
Product Name Arhgef1 (NM_001130152) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms Lbcl2; Lsc
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_001130152
ORF Size 2763 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR211176).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001130152.1, NP_001123624.1
RefSeq Size 3282 bp
RefSeq ORF 2763 bp
Locus ID 16801
Gene Summary Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation. Isoform 3 and isoform 4 do not homooligomerize and show an enhanced RhoGEF activity.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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