Dnajc10 (NM_024181) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR210690L3V
- LentiORF®
Lenti ORF particles, Dnajc10 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily C, member 10 (Dnajc10), 200ul, >10^7 TU/mL
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CNY 12,825.00
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Specifications
Product Data | |
Product Name | Dnajc10 (NM_024181) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1200006L06Rik; D2Ertd706e; ERdj5; JPDI |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_024181 |
ORF Size | 2382 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR210690).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_024181.2, NP_077143.2 |
RefSeq Size | 4054 bp |
RefSeq ORF | 2382 bp |
Locus ID | 66861 |
Gene Summary | Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.[UniProtKB/Swiss-Prot Function] |
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